Ernesto Valverde's Bilbao team punished the visitors with clinical counter-attacks, playing with the advantage of having won the first leg 1-0 in Madrid.
Saudi Arabia took third place in Group C and will feature in a fourth phase of qualifiers in October alongside Indonesia, Qatar, the United Arab Emirates, Iraq and Oman.
Arsenal snapped a season-long jinx against Newcastle United with a nervy 1-0 win in their last Premier League home game on Sunday.
A round-up of Tuesday's action in the Premier League.
A round-up of Saturday's action in the Premier League.
A summary of Saturday's action in the LaLiga, Serie A and Bundesliga.
IMAGES from the Premier League matches played on Saturday.
Real Madrid forward Vinicius Jr scored a hat-trick to help the LaLiga champions snap a two-game winless run in all competitions.
IMAGES from the Premier League matches played on Sunday.
Images from Saturday's FA Cup quarter-finals.
A round-up of Saturday's action in LaLiga, Ligue 1, Serie A and Bundesliga.
A summary of Saturday's action in the Premier League.
Defeat would have left Arsenal nine points behind Liverpool, who also have a game in hand, but the way they reacted to going behind suggests they can still be a factor in the title race.
NEUFC fashion dramatic turnaround to stun Bagan in a shootout and win historic Durand Cup title in Kolkata on Saturday
Liverpool resumed their march to a second Premier League title on Sunday with a 2-1 victory over West Ham United.
A round-up of Saturday's action in the English Premier League.
IMAGES from the South American World Cup qualifiers played on Tuesday.
Liverpool climbed to the top of the Premier League table with a 2-1 victory over struggling Wolverhampton Wanderers on Saturday.
Israel debutant Yarden Shua scored an 86th-minute winner as they upset more fancied Belgium 1-0 in Budapest on Sunday.
A round-up of Wednesday's UEFA Champions League last-16 first leg matches.
The Spaniards, looking for a record fourth Euro crown, struck twice in three minutes, with Fabian Ruiz setting up Alvaro Morata in the 29th and firing in himself a little later.
Naomi Osaka has four major titles under her belt but the second round at Flushing Meadows, Wimbledon and Roland Garros was as good as it got this year for the Japanese 26-year-old, who exited the Australian Open in the first round.
IMAGES from the Premier League matches played on Tuesday.
Manchester United substitute Jesse Lingard's superb volley in extra time secured a 2-1 win over CrystalPalace in the FA Cup final at Wembley Stadium on Saturday for their first major trophy in three years.
Images from the English Premier League matches played on Sunday night.
A summary of Tuesday's Champions League Round of 16, Second Leg, matches.
IMAGES from the UEFA Champions League matches played on Wednesday.
Leandro Trossard transformed the mood at Arsenal with the winning goal as they recovered from an early setback to beat Tottenham Hotspur 2-1 at home.
Manchester City have one just victory from their last 10 games across all competitions.
Burnley celebrated their first home match in the top division for 33 years with a shock 1-0 victory over Premier League champions Manchester United at Turf Moor on Wednesday.
Magnificent Martinez helps Inter defeat Sparta Prague 1-0
Barcelona thrashed Real Betis 5-1 on Wednesday to book their spot in the Copa del Rey quarter-finals.
Manchester United languish 14th in the standings on 19 points, their worst placing to end a calendar year since they were 15th in 1989.
Roman Pavlyuchenko scored twice as Russia came from behind to beat England 2-1 in the Euro 2008 qualifier.
Newcastle United's clash with AFC Wimbledon was postponed after flooding damaged the Wimbledon pitch on Monday.
Images from Saturday's action in the Premier League.
All the action from football matches played in Europe on Wednesday
IMAGES from the UEFA Champions League matches played on Wednesday
Give us your take on Tuesday's games in the World Cup!
Hosts France secured a second straight victory as Kiliann Sildillia struck for a 1-0 success over Guinea, while Spain and Japan reached the quarter-finals in the second matchday of the men's Olympic soccer tournament on Saturday.
